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I’m pleased to present to readers our third issue of Collaborations, a newsletter highlighting developmental disabilities research within our Mid-Atlantic Consortium (MAC), comprising the Intellectual and Developmental Disabilities Research Centers (IDDRCs) at Children’s Hospital of Philadelphia (CHOP), Children’s National Medical Center (CNMC) in Washington, D.C., and Kennedy Krieger Institute/Johns Hopkins University (KKI) in Baltimore. Our […] 
Researchers at Kennedy Krieger Institute (KKI) have been making inroads toward better understanding of brain function in children with attention-deficit/hyperactivity disorder (ADHD). One study directed by Stewart Mostofsky, M.D., director of the Laboratory for Neurocognitive and Imaging Research at KKI and an associate professor of neurology and psychiatry at the Johns Hopkins University School of […] 
Scientifically sound, well-conducted clinical trials are the gold standard of advances in medical treatment, and those who volunteer to participate in them are real heroes in modern health care. It’s important that families considering participation in research studies at one of the Mid-Atlantic Consortium research centers can do so with confidence that their safety and […] 
The pink dots represent cargos building up in neurons deficient in the protein doublecortin. A normal neuron. Working in the laboratory, researchers at Children’s National Medical Center (CNMC) have identified how a mutation in the gene doublecortin (DCX) results in a severe developmental disorder called lissencephaly. They found the protein doublecortin (Dcx), encoded […] 
Clinical geneticist and pediatrician Marni Falk, M.D., has dedicated her career to studying the genetics of human mitochondrial diseases, a group of rare conditions affecting one in every 4,000 people in the United States. Falk’s research laboratory at Children’s Hospital of Philadelphia, supported by the Eunice Kennedy Shriver National Institute of Child Health and Human […] 
A treatment developed at the Children’s Hospital of Philadelphia (CHOP) and proven to restore cognitive abilities in mice with traumatic brain injuries will soon be tested in college athletes who have sustained concussions. Traumatic brain injury (TBI) can result from any head injury, and the consequences can vary substantially in their severity and the pattern […] 
Dr. Zohn is Principal Investigator, Children’s Research Institute Center for Neuroscience Research at Children’s National Medical Center Although birth defects of the brain and spinal cord known as neural tube defects represent some of the most common birth defects, their causes remain poorly understood. Neural tube defects result when tissues that normally surround the brain […] |
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